Virus dengue denv caratteristiche, filogenesi, morfologia strutturale, patogenesi, metodi di identificazione e terapia. The virus core, within a lipid bilayer, has a lessordered structure than the external, icosahedral scaffold of 90 glycoprotein e dimers. Pdf dengue virus denv is responsible for the clinical entity known as dengue that is a great concern for economy and public health of tropical. Dengue is among the most important mosquitoborne viral disease in the world.
This flavivirus is a single strand rna virus that after their translation and replication in host cells produces three structural and seven nonstructural proteins with specific function in. Articulo original caracteristicas del virus del dengue y su. Dengue virus denv is responsible for the clinical entity known as dengue that is a great concern for economy and public health of tropical countries. A risk to anyone traveling to a tropical or subtropical region of the world where dengue virus is found. Den1, den2, den3, den4 y den5 causante del dengue 1.
In the last 50 years, dengue incidence has increased 30fold, worldwide. It is a mosquitoborne, single positivestranded rna virus of the family flaviviridae. The disease is caused by four serologically and genetically distinct viruses termed dengue virus denv 1, 2, 3 and 4. Dengue fever can be caused by any one of four types of dengue virus. Virus del dengue virus virologia free 30day trial scribd. Virus dengue denv scheda virologica ed approfondimenti. Articulo original caracteristicas del virus del dengue y.
Each year, an estimated 390 million people are infected. The three e monomers per icosahedral asymmetric unit do not have. Jul 11, 2011 dengue was created for irene bosch, ph. Five serotypes of the virus have been found, all of which can cause the full spectrum of disease.
You can be infected by at least two if not all four types at different times during your lifetime, but only once by the same type. Determinantes sociales dengue, chikungunya, zika virus. Rebeca ricohesses laboratory is studying the structural rna andor protein and transmission replication in aedes aegypti characteristics of dengue type 2 and type 3 virus variants that have produced dengue hemorrhagic fever in humans throughout the world. Need to strengthen the molecular surveillance in peru. The first structure of a flavivirus has been determined by using a combination of cryoelectron microscopy and fitting of the known structure of glycoprotein e into the electron density map. Virus del dengue o 19 hv xq yluxv lfrvdhgur gh qp dsurl. Por lo tanto, una persona puede tener hasta cuatro enfermedades por dengue durante su vida. Please use one of the following formats to cite this article in your essay, paper or report. Hay cuatro serotipos identificados, siendo nombrados del 1 al 4. This animation was an educational project for pbs tv which detailed the. Each denv has four or more genetic groups or genotypes. Nevertheless, scientists understanding of dengue virus may be simplistic, as rather than distinct antigenic groups, a continuum appears to exist. Transmission dengue virus can be transmitted from the bite of an infected aedes mosquito.
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